Liporase Injection

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Liporase Injection

Liporase Injection · Liporase Inj.

Injection Hyaluronidase

B06AA03 : HYALURONIDASE

Liporase Injection

Formulation
Colorless and transparent vial containing freeze-dried white powder
specifications
10 vials/box
How to use
Adults, children and the elderly 1. For subcutaneous injection (mass subcutaneous injection), dissolve 1,500 I.U. of hyaluronidase in water for injection or 1 mL of physiological saline injection and inject into the relevant area before starting subcutaneous injection, or inject into the tube about 2 cm above the injection needle when starting injection. When administering 500 to 1,000 mL of fluid, 1,500 I.U. of this drug is appropriate. In children and the elderly, the rate of fluid administration and total dosage must be carefully controlled, and especially in patients with renal impairment, caution must be taken to avoid fluid overload. 2. When injecting subcutaneously or intramuscularly, dissolve 1,500 I.U. of this drug directly in the injection solution. 3. Local anesthetic Use 1,500 I.U. of this drug by dissolving it in the local anesthetic injection solution to be administered. For ophthalmological use, a concentration of 15 I.U. per mL is recommended. 4. If the extravasation is diffuse rather than localized, dissolve 1,500 I.U. of this drug in 1 mL of water for injection or physiological saline injection as soon as possible after the extravasation appears and infiltrate the lesion site. 5. Hematoma Dissolve 1,500 I.U. of this drug in 1 mL of water for injection or physiological saline injection and infiltrate the affected area. Immediately before use, dissolve this drug in the injection solution to be administered with approximately 1 mL of water for injection. The subcutaneous injection solution must be isotonic with the body's extracellular fluids. This drug can be combined with commonly used intravenous solutions. Cases of large-volume subcutaneous injections used together with saline solution, 0.18% sodium chloride 4% glucose, 0.45% sodium chloride 2.5% glucose, and 5% glucose solution have been reported. Potassium is administered at 34 mmol/L in isotonic glucose or saline solution. Infusion solutions containing electrolytes are more suitable than infusion solutions that do not contain electrolytes, and should not be administered too quickly. This medicine is used in combination with morphine, diamorphine, hydromorphine, chlorpromazine, metoclopramide, promazine, dexamethasone, local anesthetic, and epinephrine.
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Product Information

Product Name

Liporase Injection

Appearance

Colorless and transparent vial containing freeze-dried white powder

Composition

10 vials/box

Importer / Seller

Sejong Medix

Active Ingredient

Hyaluronidase 1500IU

Indications
Increased penetration when administered subcutaneously, intramuscularly, local anesthetic, or subcutaneously.
Promotes reabsorption of excess fluid and blood within tissues
Dosage and Administration
Intended UseAdults, Pediatrics and Seniors
Frequency1. For subcutaneous injection (mass subcutaneous injection), dissolve 1,500 I.U. of hyaluronidase in 1 mL of water for injection or physiological saline injection and inject it into the relevant area before starting subcutaneous injection, or inject it into the tube about 2 cm above the injection needle when starting injection. When administering 500 to 1,000 mL of fluid, 1,500 I.U. of this drug is appropriate. In children and the elderly, the rate of fluid administration and total dosage must be carefully controlled, and especially in patients with renal impairment, caution must be taken to avoid fluid overload. 2. When injecting subcutaneously or intramuscularly, dissolve 1,500 I.U. of this drug directly in the injection solution. 3. Local anesthetic Use 1,500 I.U. of this drug by dissolving it in the local anesthetic injection solution to be administered. For ophthalmological use, a concentration of 15 I.U. per mL is recommended. 4. If the extravasation is diffuse rather than localized, dissolve 1,500 I.U. of this drug in 1 mL of water for injection or physiological saline injection as soon as possible after the extravasation appears and infiltrate the lesion site. 5. Hematoma Dissolve 1,500 I.U. of this drug in 1 mL of water for injection or physiological saline injection and infiltrate the affected area. Immediately before use, dissolve this drug in the injection solution to be administered with approximately 1 mL of water for injection. The subcutaneous injection solution must be isotonic with the body's extracellular fluids. This drug can be combined with commonly used intravenous solutions. Cases of large-volume subcutaneous injections used together with saline solution, 0.18% sodium chloride 4% glucose, 0.45% sodium chloride 2.5% glucose, and 5% glucose solution have been reported. Potassium is administered at 34 mmol/L in isotonic glucose or saline solution. Infusion solutions containing electrolytes are more suitable than infusion solutions that do not contain electrolytes, and should not be administered too quickly. This medicine is used in combination with morphine, diamorphine, hydromorphine, chlorpromazine, metoclopramide, promazine, dexamethasone, local anesthetic, and epinephrine.
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